重组人白细胞介素-21（人白细胞介素-21）
产品名称： 重组人白细胞介素-21（人白细胞介素-21）
英文名称： Recombinant Human Interleukin-21 (Human IL-21)
产品编号： 90120ES10
产品价格： 0
产品产地： 翌圣生物
品牌商标： Yeasen
更新时间： 2024-12-10T13:14:19
使用范围： null
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Product Information
Product Name
Cat#
Size
Price（¥）
Recombinant Human Interleukin-21 (Human IL-21)
90120ES10
10 μg
1855.00
90120ES60
100 μg
13615.00
90120ES76
500 μg
35395.00
Product Description
Interleukin-21 (IL-21) is a type I cytokine that modulates functions of T, B, natural killer (NK), and myeloid cells. IL-21 is produced by activated T follicular helper cells (Tfh), Th17 cells, and NKT cells. Tfh-derived IL-21 plays an important role in the development of humoral immunity through its autocrine effects on the Tfh cell and paracrine effects on immunoglobulin affinity maturation, plasma cell differentiation, and B cell memory responses.The 133 amino acid (aa) mature human IL-21 protein shares 63% and 61% aa sequence identity with mouse and rat IL-21 protein, respectively. Alternative splicing generates an additional isoform with a substitution of the C-terminal 16 amino acids. IL-21 shows having much relation with clinical illnesses, including cancer immunotherapy, viral infections and allergies. And it suppresses cutaneous hypersensitivity reactions by limiting allergen-specific IgE production and mast cell degranulation.
Product Properties
Synonyms
Interleukin-21, IL-21, Za11
Accession
GeneID
Source
E.coli-derived human IL-21 protein, Gln30-Ser162.
Molecular Weight
Approximately 15.4 kDa under reducing conditions.
AA Sequence
QGQDRHMIRM RQLIDIVDQL KNYVNDLVPE FLPAPEDVET NCEWSAFSCF QKAQLKSANT GNNERIINVS IKKLKRKPPS TNAGRRQKHR LTCPSCDSYE KKPPKEFLER FKSLLQKMIH QHLSSRTHGS EDS
Tag
None
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