PRKRA Peptide
产品名称: PRKRA Peptide
英文名称: PRKRA Peptide
产品编号: P2794
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PRKRA.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S18 of human PRKRA.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A heterozygous frameshift mutation in PRKRA (DYT16) associated with generalised dystonia in a German patient.
Seibler P, Djarmati A, Langpap B, Hagenah J, Schmidt A, Bruggemann N, Siebner H, Jabusch HC, Altenmuller E, Munchau A, Lohmann K, Klein C.Lancet Neurol. 2008 May;7(5):380-1.
- 2.
- Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA.
Kok KH, Ng MH, Ching YP, Jin DY.J Biol Chem. 2007 Jun 15;282(24):17649-57. Epub 2007 Apr 23.
- 3.
- PACT, a protein activator of the interferon-induced protein kinase, PKR.
Patel RC, Sen GC.EMBO J. 1998 Aug 3;17(15):4379-90.
- Entrez GeneID:
- 8575
- Protein Accession#:
- NP_003681;O75569
- Gene Name:
- PRKRA
- Gene Alias:
- DYT16,HSD14,PACT,RAX
- Gene Description:
- protein kinase, interferon-inducible double stranded RNA dependent activator
- Omim ID:
- 603424
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- protein activator of the interferon-induced protein kinase