Anti-LOXL1 Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001876P-50ul	solarbio	50ul	960.00元
K001876P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-LOXL1 Polyclonal Antibody
别名	LOL;LOXL
应用	WB
稀释比例	WB 1:1000-3000.
交叉反应	Human Mouse Rat
蛋白分子量	63kDa
Gene ID	4016
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human LOXL1
性状	液体
Public Immunogen Range	Recombinant protein of human LOXL1
Subcellular Locations	Secreted extracellular space
Swiss Prot	Q08397
克隆类型	Polyclonal Antibody
背景资料	This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.