分子量：Calculated MW: 97kDa/98kDa
Observed MW: 125kDa

细胞定位：Cell junction, Cytoplasm, Membrane, Midbody, clathrin-coated pit, cytoskeleton, postsynaptic cell membrane, postsynaptic density, synapse

稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:200

总结：Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.