CIDEA Rabbit pAb (APR27582N)
产品名称: CIDEA Rabbit pAb (APR27582N)
英文名称: CIDEA Rabbit pAb (APR27582N)
产品编号: APR27582N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
安诺伦(北京)生物科技有限公司
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- 地址 : 北京大兴经济技术开发区天骥智谷35A
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分子量:Calculated MW: 24kDa 细胞定位:Lipid droplet, Nucleus 稀释方法:IF 1:50 - 1:100 总结:This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
