FITC标记的乳腺癌易感基因相互作用蛋白1抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的乳腺癌易感基因相互作用蛋白1抗体

FITC标记的乳腺癌易感基因相互作用蛋白1抗体

商家询价

产品名称: FITC标记的乳腺癌易感基因相互作用蛋白1抗体

英文名称: Anti-BACH1/FITC

产品编号: HZ-4092R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

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 Rabbit Anti-BACH1/FITC Conjugated antibody

FITC标记的乳腺癌易感基因相互作用蛋白1抗体

 

英文名称 Anti-BACH1/FITC
中文名称 FITC标记的乳腺癌易感基因相互作用蛋白1抗体
别    名 BACH 1; BRIP1; BACH-1; BRAC 1 Associated C Terminal Helicase 1; BRCA 1 Interacting Protein 1; BRCA1 binding helicase like protein BACH1; BRCA1 interacting protein C terminal helicase 1; BRIP 1; BRIP-1; FANCJ; ATP dependent RNA helicase BRIP1; Fanconi anemia group J protein; FLJ90232; MGC126521; MGC126523; OF antibody Protein FACJ.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 81kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BACH1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009].

Function:
Transcriptional regulator that acts as repressor or activator. Binds, in-vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the bZIP family. CNC subfamily. 
Contains 1 BTB (POZ) domain. 
Contains 1 bZIP domain.

Database links:

Entrez Gene: 83990 Human

Omim: 605882 Human

SwissProt: Q9BX63 Human

Unigene: 128903 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

该基因编码属于CAN'领型的基本区域亮氨酸拉链因子家族(CNC BZIP)的转录因子。编码的蛋白质含有广泛的复合物、TrAMTrAb、BRIC-A BRAC/痘病毒和锌指(BTB/POZ)结构域,这是CNC BZIP家族成员的非典型性。这些BTB/POZ结构域有助于蛋白质-蛋白质相互作用和同源和/或异质低聚物的形成。当该编码蛋白与MafK形成异源二聚体时,它起到MAF识别元件(MARE)的阻遏作用,并抑制转录。该基因已鉴定出多个交替剪接转录变体。[ RefSeq,2009年5月提供]。