TLR8 monoclonal antibody (M04), clone 1E6
产品名称: TLR8 monoclonal antibody (M04), clone 1E6
英文名称: TLR8 monoclonal antibody (M04), clone 1E6
产品编号: H00051311-M04
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant TLR8.
- Immunogen:
- TLR8 (NP_619542, 723 a.a. ~ 825 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- RISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCVSD
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2b Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
- Download
- Application Image
- ELISA
- Entrez GeneID:
- 51311
- GeneBank Accession#:
- NM_138636
- Protein Accession#:
- NP_619542
- Gene Name:
- TLR8
- Gene Alias:
- CD288,MGC119599,MGC119600
- Gene Description:
- toll-like receptor 8
- Omim ID:
- 300366
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq
- Other Designations:
- OTTHUMP00000022930
- Gene Pathway
- Related Disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Bronchiolitis Obliterans
- Bronchiolitis, Viral
- Carcinoma, Basal Cell
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Connective Tissue Diseases
- Coronary Artery Disease
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Fetal Diseases
- Genetic Predisposition to Disease
- Hemorrhagic Fever, Crimean
- HIV Infections
- Hodgkin Disease
- Infant, Premature, Diseases