分子量：Calculated MW: 35kDa/55kDa
Observed MW: 55kDa

细胞定位：Cell membrane, Cytoplasm, Z line, cytoskeleton, myofibril, sarcolemma, sarcomere

稀释方法：WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:10 - 1:100

总结：This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.