BID polyclonal antibody
产品名称: BID polyclonal antibody
英文名称: BID polyclonal antibody
产品编号: PAB18163
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BID.
- Immunogen:
- A synthetic peptide corresponding to human BID.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Specificity:
- This antibody is specific to BID.
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Three novel Bid proteins generated by alternative splicing of the human Bid gene.
Renshaw SA, Dempsey CE, Barnes FA, Bagstaff SM, Dower SK, Bingle CD, Whyte MK.J Biol Chem. 2004 Jan 23;279(4):2846-55. Epub 2003 Oct 28.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of extracts from Jurkat cells treated with H2O2 (100 uM, 30 mins) (lane1) and Jurkat cells treated with Etoposide (25 uM, 60 mins) (lane2), using BID polyclonal antibody (Cat # PAB18163).
Peptide "+" means "peptide blocking".
- Entrez GeneID:
- 637
- Protein Accession#:
- P55957
- Gene Name:
- BID
- Gene Alias:
- FP497,MGC15319,MGC42355
- Gene Description:
- BH3 interacting domain death agonist
- Omim ID:
- 601997
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq
- Other Designations:
- BH3-interacting domain death agonist,BID isoform ES(1b),BID isoform L(2),BID isoform Si6,Human BID coding sequence,OTTHUMP00000196197,apoptic death agonist,desmocollin type 4
- Interactome
- Related Disease
- Adenocarcinoma
- Breast cancer
- Breast Neoplasms
- Carcinoma, Ductal
- Cardiovascular Diseases
- Clubfoot
- Colorectal Neoplasms
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Disease Progression
- Edema
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Kidney Failure, Chronic
- Lymphatic Metastasis
- Neoplasm Metastasis
- Stomach Neoplasms
- Tobacco Use Disorder