分子量：Calculated MW: 21kDa
Observed MW: 21KDa

细胞定位：Cell membrane, Cytoplasmic side, Golgi apparatus membrane, Lipid-anchor

稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:200

总结：This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.