GCH1 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： GCH1 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： GCH1 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00002643-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human GCH1 protein.
- Immunogen:
- GCH1 (NP_000152.1, 1 a.a. ~ 250 a.a) full-length human protein.
- Sequence:
- MEKGPVRAPAEKPRGARCSNGFPERDPPRPGPSRPAEKPPRPEAKSAQPADGWKGERPRSEEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of GCH1 expression in transfected 293T cell line (H00002643-T01) by GCH1 MaxPab polyclonal antibody.
Lane 1: GCH1 transfected lysate(27.90 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 2643
- GeneBank Accession#:
- NM_000161.2
- Protein Accession#:
- NP_000152.1
- Gene Name:
- GCH1
- Gene Alias:
- DYT14,DYT5,GCH,GTP-CH-1,GTPCH1
- Gene Description:
- GTP cyclohydrolase 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. [provided by RefSeq
- Other Designations:
- guanosine 5'-triphosphate cyclohydrolase I
- Gene Pathway
- Related Disease
- Acute Disease
- Autistic Disorder
- Cardiovascular Diseases
- Cerebrovascular Disorders
- Chromosome Aberrations
- Chromosome Deletion
- Chronic Disease
- Coronary Artery Disease
- Coronary Disease
- Diabetes Mellitus, Type 2
- Diabetic Angiopathies
- Dystonia
- Dystonic Disorders
- Edema
- Genetic Predisposition to Disease
- Hypertension
- Labor Pain
- Low Back Pain
- Mental Retardation