FITC标记的跨膜结构域边缘蛋白CEE抗体
产品名称: FITC标记的跨膜结构域边缘蛋白CEE抗体
英文名称: Anti-CEE/FITC
产品编号: HZ-6405R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-CEE/FITC Conjugated antibody
FITC标记的跨膜结构域边缘蛋白CEE抗体
英文名称 | Anti-CEE/FITC |
中文名称 | FITC标记的跨膜结构域边缘蛋白CEE抗体 |
别 名 | C7orf20; CGI 20; CGI20; Conserved edge expressed protein; Conserved edge protein; Conserved edge-expressed protein; GET 4; GET4; GET4_HUMAN; Golgi to ER traffic protein 4 homolog (S. cerevisiae); Golgi to ER traffic protein 4 homolog; Transmembrane domain recognition complex 35 kDa subunit; Transmembrane domain recognition complex 35kDa; TRC35; UPF0363 protein C7orf20; GET4_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Horse, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 36kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CEE (65-110aa) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Get4 is a 327 amino acid cytoplasmic protein that exists as two alternatively spliced isoforms. Get4 forms a multiprotein complex, known as the BAT3 complex, with UBL4A, BAT3 and ARSA. The BAT3 complex plays a role in transporting tail-anchored membrane proteins to the endoplasmic reticulum membrane. The gene encoding Get4 maps to human chromosome 7p22.3. Human chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Function: Component of the BAT3 complex, a multiprotein complexinvolved in the post-translational delivery of tail-anchored (TA)membrane proteins to the endoplasmic reticulum membrane. TAmembrane proteins, also named type II transmembrane proteins,contain a single C-terminal transmembrane region. The complex actsby facilitating TA proteins capture by ASNA1/TRC40: it is recruitedto ribosomes synthesizing membrane proteins, interacts with thetransmembrane region of newly released TA proteins, and transfersthem to ASNA1/TRC40 for targeting. Subunit: Component of the BAT3 complex, at least composed ofBAG6/BAT3, UBL4A and GET3/TRC35. Subcellular Location: Cytoplasm, cytosol. Similarity: Belongs to the GET4 family. Database links: UniProtKB/Swiss-Prot: Q7L5D6.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
GET4是一种327氨基酸的细胞质蛋白,它以两种交替剪接的亚型存在。GET4与UBL4A、BAT3和ARSA形成一个多蛋白复合物,称为BAT3复合物。BAT3复合物在运输尾部锚定膜蛋白到内质网膜中起着重要作用。编码GET4的基因定位于人类染色体722.3。人类7号染色体包含1000多个基因,包括人类基因组的5%,并与成骨不全、PAND综合征、Lissencephaly、瓜氨酸血症和SuWakman钻石综合征有关。