FITC标记的跨膜结构域边缘蛋白CEE抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的跨膜结构域边缘蛋白CEE抗体

FITC标记的跨膜结构域边缘蛋白CEE抗体

商家询价

产品名称: FITC标记的跨膜结构域边缘蛋白CEE抗体

英文名称: Anti-CEE/FITC

产品编号: HZ-6405R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

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 Rabbit Anti-CEE/FITC Conjugated antibody

FITC标记的跨膜结构域边缘蛋白CEE抗体

 

英文名称 Anti-CEE/FITC
中文名称 FITC标记的跨膜结构域边缘蛋白CEE抗体
别    名 C7orf20; CGI 20; CGI20; Conserved edge expressed protein; Conserved edge protein; Conserved edge-expressed protein; GET 4; GET4; GET4_HUMAN; Golgi to ER traffic protein 4 homolog (S. cerevisiae); Golgi to ER traffic protein 4 homolog; Transmembrane domain recognition complex 35 kDa subunit; Transmembrane domain recognition complex 35kDa; TRC35; UPF0363 protein C7orf20; GET4_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, Horse, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CEE (65-110aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Get4 is a 327 amino acid cytoplasmic protein that exists as two alternatively spliced isoforms. Get4 forms a multiprotein complex, known as the BAT3 complex, with UBL4A, BAT3 and ARSA. The BAT3 complex plays a role in transporting tail-anchored membrane proteins to the endoplasmic reticulum membrane. The gene encoding Get4 maps to human chromosome 7p22.3. Human chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Function:
Component of the BAT3 complex, a multiprotein complexinvolved in the post-translational delivery of tail-anchored (TA)membrane proteins to the endoplasmic reticulum membrane. TAmembrane proteins, also named type II transmembrane proteins,contain a single C-terminal transmembrane region. The complex actsby facilitating TA proteins capture by ASNA1/TRC40: it is recruitedto ribosomes synthesizing membrane proteins, interacts with thetransmembrane region of newly released TA proteins, and transfersthem to ASNA1/TRC40 for targeting.

Subunit:
Component of the BAT3 complex, at least composed ofBAG6/BAT3, UBL4A and GET3/TRC35.

Subcellular Location:
Cytoplasm, cytosol.

Similarity:
Belongs to the GET4 family.

Database links:
UniProtKB/Swiss-Prot: Q7L5D6.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

GET4是一种327氨基酸的细胞质蛋白,它以两种交替剪接的亚型存在。GET4与UBL4A、BAT3和ARSA形成一个多蛋白复合物,称为BAT3复合物。BAT3复合物在运输尾部锚定膜蛋白到内质网膜中起着重要作用。编码GET4的基因定位于人类染色体722.3。人类7号染色体包含1000多个基因,包括人类基因组的5%,并与成骨不全、PAND综合征、Lissencephaly、瓜氨酸血症和SuWakman钻石综合征有关。