GSK3B (Human) Recombinant Protein
产品名称: GSK3B (Human) Recombinant Protein
英文名称: GSK3B (Human) Recombinant Protein
产品编号: P4698
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human GSK3B (NP_001139628.1, 1 a.a.- 420 a.a.) full-length recombinant protein with GST-His tag expressed in Sf9 cells.
- Sequence:
- MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRGQTNNAASASASNST
- Theoretical MW (kDa):
- 76.312
- Form:
- Liquid
- Preparation Method:
- Insect cell (Sf9) expression system
- Purification:
- GST affinity chromatography
- Concentration:
- 0.276 ug/Ul
- Activity:
- 13 pmol/ug x min ATP-KM: 1.4 uM
- Storage Buffer:
- In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 15 mM reduced glutathione, 20% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing
- Quality Control Testing:
- 2 ug/lane SDS-PAGE Stained with Coomassie Blue
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 2932
- Protein Accession#:
- NP_001139628.1
- Gene Name:
- GSK3B
- Gene Alias:
- -
- Gene Description:
- glycogen synthase kinase 3 beta
- Omim ID:
- 605004
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene
- Other Designations:
- GSK3beta isoform,glycogen synthase kinase-3 beta
- Interactome
- Gene Pathway
- Alzheimer's disease
- Axon guidance
- B cell receptor signaling pathway
- Basal cell carcinoma
- Cell cycle
- Chemokine signaling pathway
- Colorectal cancer
- Endometrial cancer
- ErbB signaling pathway
- Focal adhesion
- Hedgehog signaling pathway
- Insulin signaling pathway
- Melanogenesis
- Neurotrophin signaling pathway
- Pathways in cancer
- Prostate cancer
- T cell receptor signaling pathway
- Wnt signaling pathway
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Alzheimer disease
- Amphetamine-Related Disorders
- Anorexia Nervosa
- Bipolar Disorder
- Bone Diseases
- Breast cancer
- Breast Neoplasms
- Bulimia
- Cardiovascular Diseases
- Cognition
- Dementia
- Depressive Disorder
- Depressive Disorder, Major
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Disease Progression
- Drug Toxicity