LOXL1 purified MaxPab mouse polyclonal antibody (B01P)
产品名称： LOXL1 purified MaxPab mouse polyclonal antibody (B01P)
英文名称： LOXL1 purified MaxPab mouse polyclonal antibody (B01P)
产品编号： H00004016-B01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human LOXL1 protein.
- Immunogen:
- LOXL1 (NP_005567.2, 1 a.a. ~ 574 a.a) full-length human protein.
- Sequence:
- MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSEYVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFGFGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Publication Reference
- 1.
- LOXL1 Deficiency in the Lamina Cribrosa as Candidate Susceptibility Factor for a Pseudoexfoliation-Specific Risk of Glaucoma.
Schlotzer-Schrehardt U, Hammer CM, Krysta AW, Hofmann-Rummelt C, Pasutto F, Sasaki T, Kruse FE, Zenkel M.Ophthalmology. 2012 May 23.
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of LOXL1 expression in transfected 293T cell line (H00004016-T01) by LOXL1 MaxPab polyclonal antibody.
Lane 1: LOXL1 transfected lysate(63.14 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 4016
- GeneBank Accession#:
- NM_005576.2
- Protein Accession#:
- NP_005567.2
- Gene Name:
- LOXL1
- Gene Alias:
- LOL,LOXL
- Gene Description:
- lysyl oxidase-like 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq
- Other Designations:
- lysyl oxidase homolog 1
- Related Disease
- Aneurysm, Dissecting
- Atherosclerosis
- Cardiovascular Diseases
- Cataract
- Exfoliation Syndrome
- Fetal Membranes, Premature Rupture
- Genetic Predisposition to Disease
- Glaucoma
- Glaucoma
- Glaucoma, Angle-Closure
- Glaucoma, Open-Angle
- Intracranial Aneurysm
- Low Tension Glaucoma
- Pigmentation Disorders
- Premature Birth
- Tobacco Use Disorder
- Ventricular Dysfunction, Left