TUG/ASPSCR1 Rabbit pAb (APR27433N)
产品名称: TUG/ASPSCR1 Rabbit pAb (APR27433N)
英文名称: TUG/ASPSCR1 Rabbit pAb (APR27433N)
产品编号: APR27433N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
安诺伦(北京)生物科技有限公司
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- 地址 : 北京大兴经济技术开发区天骥智谷35A
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- 所在区域 : 北京
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分子量:Calculated MW: 37kDa/54kDa/60kDa/69kDa Observed MW: 80kDa 细胞定位:Cytoplasm, Endomembrane system, Endoplasmic reticulum-Golgi intermediate compartment membrane, Nucleus, Peripheral membrane protein 稀释方法:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:100 总结:The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.
