分子量：Calculated MW: 218kDa/220kDa
Observed MW: 280kDa

细胞定位：Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center

稀释方法：WB 1:500 - 1:2000
IHC 1:100 - 1:200
IF 1:50 - 1:200

总结：The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.