CDK2AP1 (Human) Recombinant Protein (P01)
产品名称： CDK2AP1 (Human) Recombinant Protein (P01)
英文名称： CDK2AP1 (Human) Recombinant Protein (P01)
产品编号： H00008099-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human CDK2AP1 full-length ORF ( AAH34717, 1 a.a. - 115 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MSYKPNLAAHMPAAALNAAGSVHSPSTSMATSSQYRQLLSDYGPPSLGYTQGTGNSQVPQSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS
- Theoretical MW (kDa):
- 38.39
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 8099
- GeneBank Accession#:
- BC034717
- Protein Accession#:
- AAH34717
- Gene Name:
- CDK2AP1
- Gene Alias:
- DOC1,DORC1,ST19,doc-1,p12DOC-1
- Gene Description:
- cyclin-dependent kinase 2 associated protein 1
- Omim ID:
- 602198
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. [provided by RefSeq
- Other Designations:
- CDK2-associated protein 1,CDK2-associated protein 1,Deleted in oral cancer-1,cyclin-dependent kinase 2-associated protein 1,putative oral cancer suppressor