TP73 polyclonal antibody
产品名称： TP73 polyclonal antibody
英文名称： TP73 polyclonal antibody
产品编号： PAB24953
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of TP73.
- Immunogen:
- A synthetic peptide corresponding to TP73.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 70
- Reactivity:
- Human
- Specificity:
- TP73 polyclonal antibody detects endogenous levels of TP73 protein.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, pH 7.2 (0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 7161
- Gene Name:
- TP73
- Gene Alias:
- P73
- Gene Description:
- tumor protein p73
- Omim ID:
- 601990
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes tumor protein p73, which is a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53, p63, and p73 and have high sequence similarity to one another, which allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways involving direct or indirect protein interactions, resulting in regulation of the same target gene promoters or regulation of each other's promoters. The p73 protein is expressed at very low levels in normal tissues and is differentially expressed in a number of tumors. The p73 gene expresses at least 35 mRNA variants due to the use of alternate promoters, alternate translation initiation sites, and multiple splice variations. Theoretically this can account for 29 different p73 isoforms; however, the biological validity and the full-length nature of most variants have not been determined. [provided by RefSeq
- Other Designations:
- OTTHUMP00000000662,p53-like transcription factor,p53-related protein
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Alzheimer disease
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Pancreatic Ductal
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Cerebral Hemorrhage
- Chronic Disease
- Cleft Lip
- Cleft Palate
- Colorectal Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- Digestive System Neoplasms
- Disease Progression
- Endometrial Neoplasms