ATP7B/CEN13q FISH Probe
产品名称： ATP7B/CEN13q FISH Probe
英文名称： ATP7B/CEN13q FISH Probe
产品编号： FG0057
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Note:
- Hybridization position of the probes on the chromosome:
-
- Probe 1:
Size:
Fluorophore:
Location: - ATP7B
Approximately 350kb
Texas Red
13q14.3
- Probe 2:
Size:
Fluorophore:
Location: - CEN13q
Approximately 550kb
FITC
13q12.11
- Probe Gap:
- The gap between two probes is approximately 24,100 kb.
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Human stomach carcinoma (FFPE) stained with ATP7B/CEN13q FISH Probe. Human stomach carcinoma showed no ATP7B gene amplification.
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 540
- Gene Name:
- ATP7B
- Gene Alias:
- PWD,WC1,WD,WND
- Gene Description:
- ATPase, Cu++ transporting, beta polypeptide
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq
- Other Designations:
- ATPase, Cu(2+)- transporting, beta polypeptide,OTTHUMP00000040880,Wilson disease-associated protein,copper pump 2,copper-transporting ATPase 2