EPHB6 polyclonal antibody
产品名称： EPHB6 polyclonal antibody
英文名称： EPHB6 polyclonal antibody
产品编号： PAB3023
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of EPHB6.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human EPHB6.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The EphB6 receptor inhibits JNK activation in T lymphocytes and modulates T cell receptor-mediated responses.
Freywald A, Sharfe N, Rashotte C, Grunberger T, Roifman CM.J Biol Chem. 2003 Mar 21;278(12):10150-6. Epub 2003 Jan 6.
- 2.
- EphB6 crosslinking results in costimulation of T cells.
Luo H, Yu G, Wu Y, Wu J.J Clin Invest. 2002 Oct;110(8):1141-50.
- 3.
- Multiple roles of EPH receptors and ephrins in neural development.
Wilkinson DG.Nat Rev Neurosci. 2001 Mar;2(3):155-64.
- Application Image
- Western Blot
- Immunohistochemistry
- ELISA
- Entrez GeneID:
- 2051
- Protein Accession#:
- NP_031964;O15197
- Gene Name:
- EPHB6
- Gene Alias:
- HEP,MGC129910,MGC129911
- Gene Description:
- EPH receptor B6
- Omim ID:
- 602757
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands. [provided by RefSeq
- Other Designations:
- ephrin receptor EphB6
- Gene Pathway